Compound Detail
CHEMBL164206
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Basic Information
| ChEMBL ID | CHEMBL164206 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | BUUZKUBXYMPJOM-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
390.6
MW (Da)
5.90
ALogP
4
HBA
0
HBD
34.0
PSA (Ų)
0.53
QED
1
Ro5 Violations
6
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 8.64
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Corticotropin-releasing factor receptor 1 CHEMBL4649 | Ki | 8.64 | 8.64 | 2.3 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Corticotropin-releasing factor receptor 1 | Ki | = | 2.3 | nM | 8.64 | Compound was tested in vitro for its ability to displace [125 I]Tyr-sauvagine fr... | 10782669 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 10782669 | 10.1016/s0960-894x(00)00071-8 | Corticotropin-releasing factor receptor 1 | 1 |
Data from ChEMBL 36 via Core Engine