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Compound Detail

CHEMBL1644700

SODIUM PERCHLORATE
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[Na+].[O-][Cl+3]([O-])([O-])[O-]
ChEMBL ↗ Properties Compare Identifier

Basic Information

ChEMBL ID CHEMBL1644700
Name SODIUM PERCHLORATE
Phase Preclinical
Structure Type MOL
InChI Key BAZAXWOYCMUHIX-UHFFFAOYSA-M
1
Targets
6
Activities
2
Assay Types
0
PK Parameters
20
Publications
0
Known Names

Molecular Properties

122.4
MW (Da)

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula ClNaO4
MW 122.44

Activity Summary

Ki 4 meas.
IC50 2 meas. best 7.0

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Sodium/iodide cotransporter
CHEMBL2331047
 IC50 7.0 7.0 100.0 2

Activity Data Samples

Top measurements by pChEMBL value

Target Type Rel. Value Units pChEMBL Assay PubMed
Sodium/iodide cotransporter IC50 = 100.0 nM 7.0 inhibition of sodium iodide symporter in rat FRTL5 cells after 1 hr by arsenic/c... 23454514
Sodium/iodide cotransporter IC50 = 100.0 nM 7.0 Inhibition of sodium iodide symporter in rat FRTL5 cells assessed as inhibition ... -

Literature References

PubMed DOI Target Context # Activities
27914949 10.1016/j.bmc.2016.11.021 Unchecked 4
23200251 10.1016/j.bmcl.2012.10.103 Unchecked 3
26145820 10.1016/j.bmc.2015.06.021 Unchecked 3
26254943 10.1016/j.bmcl.2015.07.043 Staphylococcus aureus 3
22835873 10.1016/j.bmcl.2012.06.106 Unchecked 2
23790722 10.1016/j.bmc.2013.05.058 Unchecked 2
23414807 10.1016/j.bmcl.2013.01.084 Unchecked 2
24461298 10.1016/j.bmcl.2013.12.124 Unchecked 2
23414801 10.1016/j.bmcl.2013.01.087 Unchecked 2
28754318 10.1016/j.bmc.2017.07.033 Unchecked 2
25168748 10.1016/j.bmcl.2014.08.014 Unchecked 2
21570835 10.1016/j.bmcl.2011.04.105 Unchecked 2
26254943 10.1016/j.bmcl.2015.07.043 Staphylococcus epidermidis 2
28238511 10.1016/j.bmc.2017.02.032 Unchecked 2
23072866 10.1016/j.bmcl.2012.09.065 Carbonic anhydrase 2 1
23072866 10.1016/j.bmcl.2012.09.065 Carbonic anhydrase 1 1
22227210 10.1016/j.bmcl.2011.12.085 Astrosclerin-3 1
22227210 10.1016/j.bmcl.2011.12.085 Carbonic anhydrase 1 1
21570835 10.1016/j.bmcl.2011.04.105 Carbonic anhydrase 1 1
21377369 10.1016/j.bmc.2011.02.015 Carbonic anhydrase 2 1

Data from ChEMBL 36 via Core Engine