Compound Detail
CHEMBL1644787
BENZOCAMPHORIN B Enter ChEMBL ID:
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Basic Information
| ChEMBL ID | CHEMBL1644787 |
| Name | BENZOCAMPHORIN B |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | OJOWAFWCUHHNHF-UHFFFAOYSA-N |
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
260.3
MW (Da)
2.67
ALogP
4
HBA
0
HBD
36.9
PSA (Ų)
0.77
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 4.92
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Nitric oxide synthase, inducible CHEMBL3464 | IC50 | 4.92 | 4.92 | 12100.0 | 1 |
| Unchecked CHEMBL612545 | IC50 | 4.84 | 4.84 | 14400.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Nitric oxide synthase, inducible | IC50 | = | 12100.0 | nM | 4.92 | Inhibition of iNOS in mouse BV2 microglial cells assessed as NO production | 21115251 |
| Unchecked | IC50 | = | 14400.0 | nM | 4.84 | Inhibition of NOX in fMLP-induced PMN cells assessed as NO production | 21115251 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 21115251 | 10.1016/j.bmc.2010.10.032 | Unchecked | 2 |
| 21115251 | 10.1016/j.bmc.2010.10.032 | Nitric oxide synthase, inducible | 1 |
Data from ChEMBL 36 via Core Engine