Compound Detail
CHEMBL1644878
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL1644878 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | YPCGMUISWUIAPN-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
386.4
MW (Da)
1.63
ALogP
10
HBA
1
HBD
117.8
PSA (Ų)
0.60
QED
0
Ro5 Violations
7
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 5.39
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | IC50 | 5.39 | 5.39 | 4100.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | IC50 | = | 4100.0 | nM | 5.39 | Inhibition of tubulin polymerization | 21167709 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 21167709 | 10.1016/j.bmcl.2010.11.113 | SH-SY5Y | 4 |
| 21167709 | 10.1016/j.bmcl.2010.11.113 | Unchecked | 1 |
Data from ChEMBL 36 via Core Engine