Compound Detail
CHEMBL1652130
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Basic Information
| ChEMBL ID | CHEMBL1652130 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | FEWMJLHUMQWSNW-UHFFFAOYSA-N |
1
Targets
5
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
356.3
MW (Da)
5.13
ALogP
3
HBA
0
HBD
17.8
PSA (Ų)
0.56
QED
1
Ro5 Violations
1
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 5 meas. best 5.54
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Coxsackievirus B3 CHEMBL613554 | EC50 | 5.54 | 5.484 | 2900.0 | 5 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Coxsackievirus B3 | EC50 | = | 2900.0 | nM | 5.54 | Antiviral activity against Human coxsackievirus B3 harboring wild type nonstruct... | 19237651 |
| Coxsackievirus B3 | EC50 | = | 2900.0 | nM | 5.54 | Antiviral activity against Human coxsackievirus B3 harboring nonstructural prote... | 19237651 |
| Coxsackievirus B3 | EC50 | = | 3400.0 | nM | 5.47 | Antiviral activity against Human coxsackievirus B3 harboring nonstructural prote... | 19237651 |
| Coxsackievirus B3 | EC50 | = | 3600.0 | nM | 5.44 | Antiviral activity against Human coxsackievirus B3 harboring nonstructural prote... | 19237651 |
| Coxsackievirus B3 | EC50 | = | 3700.0 | nM | 5.43 | Antiviral activity against Human coxsackievirus B3 harboring nonstructural prote... | 19237651 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 19237651 | 10.1128/aac.00934-08 | Coxsackievirus B3 | 5 |
Data from ChEMBL 36 via Core Engine