Compound Detail
CHEMBL165537
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Basic Information
| ChEMBL ID | CHEMBL165537 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | VNMPOUHKGUHIJC-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
347.4
MW (Da)
1.54
ALogP
6
HBA
2
HBD
113.8
PSA (Ų)
0.67
QED
0
Ro5 Violations
7
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 5.9
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Histamine H3 receptor CHEMBL4124 | Ki | 5.9 | 5.9 | 1258.9 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Histamine H3 receptor | Ki | = | 1258.93 | nM | 5.9 | Binding affinity against H3 receptor in rat cerebral cortex membranes was evalua... | - |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| - | 10.1016/0960-894X(96)00122-9 | Histamine H3 receptor | 2 |
Data from ChEMBL 36 via Core Engine