Compound Detail
CHEMBL166115
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Basic Information
| ChEMBL ID | CHEMBL166115 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | FBKNMNSUKXGQCW-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
280.4
MW (Da)
3.82
ALogP
4
HBA
0
HBD
25.4
PSA (Ų)
0.71
QED
0
Ro5 Violations
7
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 6.15
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Muscarinic acetylcholine receptor M1 CHEMBL276 | IC50 | 6.15 | 6.15 | 715.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Muscarinic acetylcholine receptor M1 | IC50 | = | 715.0 | nM | 6.15 | Displacement of [3H]-Pz (pirenzepine) from the muscarinic receptor M1 of the rat... | - |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| - | 10.1016/S0960-894X(00)80536-3 | Muscarinic acetylcholine receptor | 1 |
| - | 10.1016/S0960-894X(00)80536-3 | Muscarinic acetylcholine receptor M1 | 1 |
| - | 10.1016/S0960-894X(00)80536-3 | Oryctolagus cuniculus | 1 |
Data from ChEMBL 36 via Core Engine