Compound Detail
CHEMBL167368
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Basic Information
| ChEMBL ID | CHEMBL167368 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | FCGPWKCJPCLCKH-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
365.4
MW (Da)
3.20
ALogP
5
HBA
1
HBD
99.6
PSA (Ų)
0.82
QED
0
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 7.82
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Carbonic anhydrase 2 CHEMBL205 | IC50 | 7.82 | 7.82 | 15.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Carbonic anhydrase 2 | IC50 | = | 15.0 | nM | 7.82 | Compound was tested for inhibition of human carbonic anhydrase (hCA II) | 12617909 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 12617909 | 10.1016/s0960-894x(03)00009-x | Carbonic anhydrase 2 | 1 |
Data from ChEMBL 36 via Core Engine