Compound Detail
CHEMBL16834
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Basic Information
| ChEMBL ID | CHEMBL16834 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | FQLSDZRDGGRNBU-VUWPPUDQSA-N |
1
Targets
1
Activities
1
Assay Types
1
PK Parameters
2
Publications
0
Known Names
Molecular Properties
221.3
MW (Da)
1.02
ALogP
3
HBA
1
HBD
70.1
PSA (Ų)
0.76
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 8.96
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Dipeptidyl peptidase 4 CHEMBL284 | Ki | 8.96 | 8.96 | 1.1 | 1 |
Pharmacokinetic Data
| Parameter | Value | Units | Species |
|---|---|---|---|
| T1/2 | 48.0 | hr | - |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Dipeptidyl peptidase 4 | Ki | = | 1.1 | nM | 8.96 | In vitro test for inhibitory activity against human dipeptidyl peptidase IV. | - |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| - | 10.1016/0960-894X(96)00190-4 | Dipeptidyl peptidase 4 | 1 |
| - | 10.1016/0960-894X(96)00190-4 | ADMET | 1 |
Data from ChEMBL 36 via Core Engine