Compound Detail
CHEMBL1684165
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Basic Information
| ChEMBL ID | CHEMBL1684165 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | PWHLBCGJJAIRKH-WSJIBOKFSA-M |
| Parent Compound | CHEMBL1739271 |
| Active Moiety | CHEMBL1739271 |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
225.3
MW (Da)
-2.95
ALogP
5
HBA
5
HBD
101.2
PSA (Ų)
0.33
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 4.28
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Sucrase-isomaltase, intestinal CHEMBL3114 | IC50 | 4.28 | 4.28 | 52900.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Sucrase-isomaltase, intestinal | IC50 | = | 52900.0 | nM | 4.28 | Inhibition of rat intestinal isomaltase | 21345683 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 21345683 | 10.1016/j.bmc.2011.01.052 | Sucrase-isomaltase, intestinal | 3 |
| 21345683 | 10.1016/j.bmc.2011.01.052 | Acidic alpha-glucosidase | 1 |
Data from ChEMBL 36 via Core Engine