Compound Detail
CHEMBL169838
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Basic Information
| ChEMBL ID | CHEMBL169838 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | ZMXAHDWFFGRSOY-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
386.2
MW (Da)
4.29
ALogP
5
HBA
0
HBD
60.1
PSA (Ų)
0.67
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 7.54
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Corticotropin-releasing factor receptor 1 CHEMBL4649 | Ki | 7.54 | 7.54 | 29.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Corticotropin-releasing factor receptor 1 | Ki | = | 29.0 | nM | 7.54 | Binding affinity was determined against corticotropin releasing factor receptor ... | 10072680 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 10072680 | 10.1021/jm980223o | Corticotropin-releasing factor receptor 1 | 1 |
Data from ChEMBL 36 via Core Engine