Compound Detail
CHEMBL170120
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Basic Information
| ChEMBL ID | CHEMBL170120 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | YUTZKTSDQCEUQO-ZGTHDJBKSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
448.6
MW (Da)
6.36
ALogP
5
HBA
1
HBD
72.8
PSA (Ų)
0.11
QED
1
Ro5 Violations
18
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 7.96
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Protein kinase C alpha type CHEMBL299 | Ki | 7.96 | 7.96 | 11.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Protein kinase C alpha type | Ki | = | 11.0 | nM | 7.96 | Binding Affinity against protein kinase C alpha | 10715158 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 10715158 | 10.1021/jm9904607 | Protein kinase C alpha type | 2 |
| 10715158 | 10.1021/jm9904607 | C3H 10T1/2 | 1 |
Data from ChEMBL 36 via Core Engine