Compound Detail
CHEMBL17096
PALASONIN Enter ChEMBL ID:
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Basic Information
| ChEMBL ID | CHEMBL17096 |
| Name | PALASONIN |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | RJXMWQSSXZMNIT-ZZECOBPMSA-N |
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
182.2
MW (Da)
0.25
ALogP
4
HBA
0
HBD
52.6
PSA (Ų)
0.40
QED
0
Ro5 Violations
0
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 6.92
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Serine-threonine protein phosphatase 2A regulatory subunit CHEMBL2669 | IC50 | 6.92 | 6.92 | 120.0 | 1 |
| Unchecked CHEMBL612545 | IC50 | 6.16 | 6.16 | 700.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Serine-threonine protein phosphatase 2A regulatory subunit | IC50 | = | 120.0 | nM | 6.92 | Exogenous inhibition concentration of Serine/threonine protein phosphatase 2A (P... | 11881984 |
| Unchecked | IC50 | = | 700.0 | nM | 6.16 | Exogenous inhibition of Serine/threonine protein phosphatase 1 (PP1) | 11881984 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 11881984 | 10.1021/jm010066k | Unchecked | 2 |
| 11881984 | 10.1021/jm010066k | Serine-threonine protein phosphatase 2A regulatory subunit | 1 |
Data from ChEMBL 36 via Core Engine