Compound Detail
CHEMBL1711405
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Basic Information
| ChEMBL ID | CHEMBL1711405 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | CNFDNZNQIKNQLC-UHFFFAOYSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
340.2
MW (Da)
1.70
ALogP
3
HBA
2
HBD
61.4
PSA (Ų)
0.82
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 5.35
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| NACHT, LRR and PYD domains-containing protein 3 CHEMBL1741208 | IC50 | 5.35 | 4.99 | 4440.0 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| NACHT, LRR and PYD domains-containing protein 3 | IC50 | = | 4440.0 | nM | 5.35 | PUBCHEM_BIOASSAY: Dose Response confirmation of inhibitors of NALP3 in yeast usi... | - |
| NACHT, LRR and PYD domains-containing protein 3 | IC50 | = | 23300.0 | nM | 4.63 | PUBCHEM_BIOASSAY: Dose Response confirmation of uHTS for the identification of i... | - |
Data from ChEMBL 36 via Core Engine