Compound Detail
CHEMBL1723657
6-CHLORONICOTINIC ACID Enter ChEMBL ID:
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Basic Information
| ChEMBL ID | CHEMBL1723657 |
| Name | 6-CHLORONICOTINIC ACID |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | UAWMVMPAYRWUFX-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
6
Publications
0
Known Names
Molecular Properties
157.6
MW (Da)
1.43
ALogP
2
HBA
1
HBD
50.2
PSA (Ų)
0.63
QED
0
Ro5 Violations
1
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 9.25
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Nicotinate phosphoribosyltransferase CHEMBL4523354 | Ki | 9.25 | 9.25 | 0.6 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Nicotinate phosphoribosyltransferase | Ki | = | 0.56 | nM | 9.25 | Inhibition of NAPRT (unknown origin) | - |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 21476569 | 10.1021/jf200485k | Aldehyde oxidase 1 | 2 |
| 21476569 | 10.1021/jf200485k | Unchecked | 2 |
| 21476569 | 10.1021/jf200485k | Tyrosinase | 2 |
| 24499135 | 10.1021/jm401808n | Staphylococcus aureus | 2 |
| 21476569 | 10.1021/jf200485k | Catalase | 1 |
| 24499135 | 10.1021/jm401808n | Quinolone resistance protein NorA | 1 |
Data from ChEMBL 36 via Core Engine