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Compound Detail

CHEMBL1733174

MOSAPRIDE CITRATE
🧪 Phase III
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🧪 Phase III
CCOc1cc(N)c(Cl)cc1C(=O)NCC1CN(Cc2ccc(F)cc2)CCO1.O=C(O)CC(O)(CC(=O)O)C(=O)O

Basic Information

ChEMBL ID CHEMBL1733174
Name MOSAPRIDE CITRATE
Phase Phase III
Structure Type MOL
InChI Key HUZTYZBFZKRPFG-UHFFFAOYSA-N
Parent Compound CHEMBL60889
Active Moiety CHEMBL60889

Known Names

AS-4370 Gasmotin Mosapride citrate Rimopride citrate
0
Targets
0
Activities
0
Assay Types
0
PK Parameters
16
Publications
4
Known Names
1
Indications

Molecular Properties

421.9
MW (Da)
3.09
ALogP
5
HBA
2
HBD
76.8
PSA (Ų)
0.67
QED
0
Ro5 Violations
7
Rot. Bonds

Drug Information

Molecule Type Small molecule
Chirality Racemic
USAN Stem -pride

Extended Properties

Molecular Formula C27H33ClFN3O10
MW 614.02
Aromatic Rings 2
Heavy Atoms 29
NP-Likeness -1.83

Indications

Dyspepsia

Literature References

PubMed DOI Target Context # Activities
- 10.6019/CHEMBL4495565 SARS-CoV-2 4
1995885 10.1021/jm00106a023 Canis familiaris 3
- 10.6019/CHEMBL4495564 Replicase polyprotein 1ab 2
1995885 10.1021/jm00106a023 D(2) dopamine receptor 1
1995885 10.1021/jm00106a023 Serotonin 1 (5-HT1) receptor 1
1995885 10.1021/jm00106a023 Serotonin 2 (5-HT2) receptor 1
1995885 10.1021/jm00106a023 Adrenergic receptor alpha-1 1
1995885 10.1021/jm00106a023 Adrenergic receptor alpha-2 1
- 10.21203/rs.3.rs-23951/v1 SARS-CoV-2 1
- 10.6019/CHEMBL4513141 Candida albicans 1
- 10.6019/CHEMBL4513141 Cryptococcus neoformans 1
- 10.6019/CHEMBL4513141 Escherichia coli 1
- 10.6019/CHEMBL4513141 Klebsiella pneumoniae 1
- 10.6019/CHEMBL4513141 Pseudomonas aeruginosa 1
- 10.6019/CHEMBL4513141 Acinetobacter baumannii 1
- 10.6019/CHEMBL4513141 Staphylococcus aureus 1

Data from ChEMBL 36 via Core Engine