Compound Detail
CHEMBL1741384
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Basic Information
| ChEMBL ID | CHEMBL1741384 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | YYZCEOGYVYXDPC-BJMVGYQFSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
182.2
MW (Da)
0.57
ALogP
2
HBA
3
HBD
66.2
PSA (Ų)
0.36
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 5.38
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Tyrosinase CHEMBL3318 | IC50 | 5.38 | 5.38 | 4148.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Tyrosinase | IC50 | = | 4148.0 | nM | 5.38 | Inhibition of mushroom tyrosinase diphenolase activity using L-dopa as substrate | 31015905 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 31015905 | 10.1039/C9MD00005D | Tyrosinase | 1 |
Data from ChEMBL 36 via Core Engine