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Compound Detail

CHEMBL1743078

TEPLIZUMAB
💊 Approved Drug
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💊 Approved Drug
No structure available

Basic Information

ChEMBL ID CHEMBL1743078
Name TEPLIZUMAB
Phase Approved
Structure Type SEQ
Therapeutic ✓ Yes

Known Names

hOKT3 gamma 1 (Ala-Ala) HOKT3-GAMMA-1 (ALA-ALA) HUMANIZED OKT3 Humanzied OKT3 MGA-031 MGA031 PRV-031 PRV031 Teplizumab Teplizumab mzwv Teplizumab-mzwv Tzield
0
Targets
0
Activities
0
Assay Types
0
PK Parameters
0
Publications
12
Known Names
3
Indications
1
Mechanisms

Drug Information

Molecule Type Antibody
First Approval 2022
Availability Prescription
Chirality Single Enantiomer

Routes of Administration

Parenteral

Flags

First in Class
USAN Stem -mab; -mab
USAN Year 2006

Mechanism of Action

Mechanism Action Type Target Direct Efficacy
T-cell surface glycoprotein CD3 epsilon chain other OTHER T-cell surface glycoprotein CD3 epsilon chain

Indications

Diabetes Mellitus, Type 1 Glucose Intolerance Psoriasis

ATC Classification

A10XX01
teplizumab
Level 1: ALIMENTARY TRACT AND METABOLISM
Level 2: DRUGS USED IN DIABETES

Data from ChEMBL 36 via Core Engine