Compound Detail
CHEMBL1760549
N-ISOFERULOYL SEROTONIN Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL1760549 |
| Name | N-ISOFERULOYL SEROTONIN |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | ANXSVAOJTRHGIE-XVNBXDOJSA-N |
2
Targets
2
Activities
2
Assay Types
0
PK Parameters
5
Publications
0
Known Names
Molecular Properties
352.4
MW (Da)
2.96
ALogP
4
HBA
4
HBD
94.6
PSA (Ų)
0.51
QED
0
Ro5 Violations
6
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 4.46
IC50 1 meas. best 5.27
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Tyrosinase CHEMBL3318 | IC50 | 5.27 | 5.27 | 5400.0 | 1 |
| Radical scavenging activity CHEMBL613712 | EC50 | 4.46 | 4.46 | 35100.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Tyrosinase | IC50 | = | 5400.0 | nM | 5.27 | Inhibition of mushroom tyrosinase after 25 mins by spectrophotometry | 21377874 |
| Radical scavenging activity | EC50 | = | 35100.0 | nM | 4.46 | Antioxidant activity assessed as DPPH radical scavenging activity by spectrophot... | 21377874 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| - | 10.1007/s00044-011-9699-9 | Alpha-glucosidase MAL62 | 2 |
| 21377874 | 10.1016/j.bmcl.2011.02.028 | Radical scavenging activity | 1 |
| 21377874 | 10.1016/j.bmcl.2011.02.028 | Tyrosinase | 1 |
| 22386242 | 10.1016/j.bmcl.2012.02.002 | Prostaglandin G/H synthase 1 | 1 |
| 22386242 | 10.1016/j.bmcl.2012.02.002 | Prostaglandin G/H synthase 2 | 1 |
Data from ChEMBL 36 via Core Engine