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Compound Detail

CHEMBL1765380

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CC(C)(O)/C=C/C(=O)[C@](C)(O)[C@H]1[C@H](O)C[C@@]2(C)[C@@H]3CC=C4[C@@H](C=C(O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)C(=O)C4(C)C)[C@]3(C)C(=O)C[C@]12C

Basic Information

ChEMBL ID CHEMBL1765380
Phase Preclinical
Structure Type MOL
InChI Key LIIOJBIJVPGVGO-JZZAZZIQSA-N
1
Targets
4
Activities
2
Assay Types
0
PK Parameters
10
Publications
0
Known Names

Molecular Properties

676.8
MW (Da)
0.88
ALogP
12
HBA
7
HBD
211.3
PSA (Ų)
0.15
QED
3
Ro5 Violations
7
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

Natural Product First in Class Prodrug

Extended Properties

Molecular Formula C36H52O12
MW 676.80
Aromatic Rings 0
Heavy Atoms 48
NP-Likeness 2.92

Activity Summary

EC50 2 meas. best 5.38
IC50 2 meas.

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
NON-PROTEIN TARGET
CHEMBL3879801
EC50 5.38 5.38 4150.0 1

Activity Data Samples

Top measurements by pChEMBL value

Target Type Rel. Value Units pChEMBL Assay PubMed
NON-PROTEIN TARGET EC50 = 4150.0 nM 5.38 Antiproliferative activity against serum-stimulated rat HSC-T6 cells after 24 hr... 21459003

Literature References

Data from ChEMBL 36 via Core Engine