Compound Detail
CHEMBL1767116
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Basic Information
| ChEMBL ID | CHEMBL1767116 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | LRIKJKQEONMJCX-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
454.1
MW (Da)
5.47
ALogP
4
HBA
1
HBD
59.7
PSA (Ų)
0.53
QED
1
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 6.18
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Solute carrier family 22 member 12 CHEMBL6120 | IC50 | 6.18 | 6.18 | 667.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Solute carrier family 22 member 12 | IC50 | = | 667.0 | nM | 6.18 | Inhibition of human URAT1 expressed in xenopus oocyte assessed as inhibition of ... | 21449597 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 21449597 | 10.1021/jm1015022 | Solute carrier family 22 member 12 | 2 |
Data from ChEMBL 36 via Core Engine