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Compound Detail

CHEMBL1783640

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Cc1cc(C2(c3ccc(OCC(=O)C(C)(C)C)c(C)c3)CCCC2)ccc1OCC(=O)C(C)(C)C

Basic Information

ChEMBL ID CHEMBL1783640
Phase Preclinical
Structure Type MOL
InChI Key YMABITBDEMOCPZ-UHFFFAOYSA-N
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names

Molecular Properties

478.7
MW (Da)
7.15
ALogP
4
HBA
0
HBD
52.6
PSA (Ų)
0.40
QED
1
Ro5 Violations
8
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C31H42O4
MW 478.67
Aromatic Rings 2
Heavy Atoms 35
NP-Likeness -0.15

Activity Summary

EC50 1 meas. best 4.89

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Bovine viral diarrhea virus 1
CHEMBL612571
EC50 4.89 4.89 13000.0 1

Activity Data Samples

Top measurements by pChEMBL value

Literature References

PubMed DOI Target Context # Activities
19447037 10.1016/j.bmcl.2009.04.137 Bovine viral diarrhea virus 1 1
19447037 10.1016/j.bmcl.2009.04.137 ADMET 1

Data from ChEMBL 36 via Core Engine