Assay Detail
Functional
CHEMBL1785504
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Antiviral activity against BVDV1 Nose infected in MDBK cells assessed as inhibition of virus replication-induced cell destruction
14
Total Activities
14
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Bovine viral diarrhea virus 1 |
| Cell Type | MDBK |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Target
Bovine viral diarrhea virus 1 (CHEMBL612571) ↗| Type | ORGANISM |
| Organism | Bovine viral diarrhea virus 1 |
Publication
Discovery of diphenylmethane analogs as anti-bovine diarrhea viral agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 14 | 4.97 | 5.21 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1783643 | — | — | 1 | 5.21 |
| CHEMBL1783639 | — | — | 1 | 5.20 |
| CHEMBL1783644 | — | — | 1 | 5.10 |
| CHEMBL1783642 | — | — | 1 | 5.08 |
| CHEMBL1782330 | — | — | 1 | 5.07 |
| CHEMBL198213 | — | — | 1 | 5.05 |
| CHEMBL250292 | — | — | 1 | 5.00 |
| CHEMBL1782331 | — | — | 1 | 5.00 |
| CHEMBL1782333 | — | — | 1 | 4.92 |
| CHEMBL1783640 | — | — | 1 | 4.89 |
| CHEMBL1783641 | — | — | 1 | 4.89 |
| CHEMBL1782328 | — | — | 1 | 4.60 |
| CHEMBL1782329 | — | — | 1 | 4.55 |
| CHEMBL1782332 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1783643 | — | EC50 | = | 6200.0 | nM | 5.21 |
| CHEMBL1783639 | — | EC50 | = | 6300.0 | nM | 5.20 |
| CHEMBL1783644 | — | EC50 | = | 8000.0 | nM | 5.10 |
| CHEMBL1783642 | — | EC50 | = | 8400.0 | nM | 5.08 |
| CHEMBL1782330 | — | EC50 | = | 8600.0 | nM | 5.07 |
| CHEMBL198213 | — | EC50 | = | 8900.0 | nM | 5.05 |
| CHEMBL250292 | — | EC50 | = | 10000.0 | nM | 5.00 |
| CHEMBL1782331 | — | EC50 | = | 10000.0 | nM | 5.00 |
| CHEMBL1782333 | — | EC50 | = | 12000.0 | nM | 4.92 |
| CHEMBL1783640 | — | EC50 | = | 13000.0 | nM | 4.89 |
| CHEMBL1783641 | — | EC50 | = | 12800.0 | nM | 4.89 |
| CHEMBL1782328 | — | EC50 | = | 25000.0 | nM | 4.60 |
| CHEMBL1782329 | — | EC50 | = | 28000.0 | nM | 4.55 |
| CHEMBL1782332 | — | EC50 | > | 42000.0 | nM | - |