Compound Detail
CHEMBL180844
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Basic Information
| ChEMBL ID | CHEMBL180844 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | OCCZRIQZJSXKQT-SDNWHVSQSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
428.8
MW (Da)
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 6.3
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Leishmania chagasi CHEMBL612790 | IC50 | 6.3 | 6.3 | 500.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Leishmania chagasi | IC50 | = | 500.0 | nM | 6.3 | Antileishmanial activity against amastigotes stage of Leishmania chagasi MHOM/BR... | 31098003 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 15664852 | 10.1016/j.bmcl.2004.11.012 | Cathepsin B | 1 |
| 15664852 | 10.1016/j.bmcl.2004.11.012 | HL-60 | 1 |
| 31098003 | 10.1021/acsmedchemlett.9b00060 | Leishmania chagasi | 1 |
Data from ChEMBL 36 via Core Engine