Compound Detail
CHEMBL1811947
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Basic Information
| ChEMBL ID | CHEMBL1811947 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | VXARBLVMQSRVFX-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
555.7
MW (Da)
6.47
ALogP
9
HBA
2
HBD
134.6
PSA (Ų)
0.10
QED
2
Ro5 Violations
25
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 10.82
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Human immunodeficiency virus 1 CHEMBL378 | EC50 | 10.82 | 10.82 | 0.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Human immunodeficiency virus 1 | EC50 | = | 0.015 | nM | 10.82 | Antiviral activity against HIV 1 LAI infected in MT2 cells | 21565516 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 21565516 | 10.1016/j.bmc.2011.04.016 | Human immunodeficiency virus 1 | 1 |
Data from ChEMBL 36 via Core Engine