Compound Detail
CHEMBL18135
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL18135 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | KWFNQPQHPUCUAI-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
5
Publications
0
Known Names
Molecular Properties
260.2
MW (Da)
3.17
ALogP
2
HBA
0
HBD
20.3
PSA (Ų)
0.58
QED
0
Ro5 Violations
6
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 5.26
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| UV4 CHEMBL612800 | IC50 | 5.26 | 5.26 | 5500.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| UV4 | IC50 | = | 5500.0 | nM | 5.26 | In vitro cytotoxicity against transformed chinese hamster fibroblast line UV4. | 2319563 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 2319563 | 10.1021/jm00166a015 | P388 | 3 |
| 2319563 | 10.1021/jm00166a015 | ADMET | 2 |
| 2319563 | 10.1021/jm00166a015 | CHO-AA8 | 1 |
| 2319563 | 10.1021/jm00166a015 | UV4 | 1 |
| 2319563 | 10.1021/jm00166a015 | Unchecked | 1 |
Data from ChEMBL 36 via Core Engine