Compound Detail
CHEMBL1822917
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Basic Information
| ChEMBL ID | CHEMBL1822917 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | GZVMGUGHKXWURO-NKGQWRHHSA-N |
| Parent Compound | CHEMBL1852481 |
| Active Moiety | CHEMBL1852481 |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
281.4
MW (Da)
2.69
ALogP
3
HBA
3
HBD
52.5
PSA (Ų)
0.65
QED
0
Ro5 Violations
0
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 2 meas. best 4.66
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | Ki | 4.66 | 4.36 | 22000.0 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | Ki | = | 22000.0 | nM | 4.66 | Displacement of [3H]SCH23390 from dopamine D1-like receptor in pig striatal tiss... | 21862338 |
| Unchecked | Ki | = | 88000.0 | nM | 4.06 | Displacement of [3H]-N-methylspiperone from dopamine D2-like receptor in pig str... | 21862338 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 21862338 | 10.1016/j.bmc.2011.07.057 | Unchecked | 2 |
Data from ChEMBL 36 via Core Engine