Compound Detail
CHEMBL1829658
DALBERGIN Enter ChEMBL ID:
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Basic Information
| ChEMBL ID | CHEMBL1829658 |
| Name | DALBERGIN |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | AZELSOYQOIUPBZ-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
6
Publications
0
Known Names
Molecular Properties
268.3
MW (Da)
3.17
ALogP
4
HBA
1
HBD
59.7
PSA (Ų)
0.73
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 8.99
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Calvarial osteoblast CHEMBL4296516 | EC50 | 8.99 | 8.99 | 1.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Calvarial osteoblast | EC50 | = | 1.015 | nM | 8.99 | Osteogenic activity in rat calvarial osteoblast cells assessed as induction of c... | 24803361 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 24803361 | 10.1016/j.bmcl.2014.04.056 | Calvarial osteoblast | 6 |
| 21784631 | 10.1016/j.bmcl.2011.06.036 | NON-PROTEIN TARGET | 2 |
| 21784631 | 10.1016/j.bmcl.2011.06.036 | A549 | 1 |
| 21784631 | 10.1016/j.bmcl.2011.06.036 | DU-145 | 1 |
| 21784631 | 10.1016/j.bmcl.2011.06.036 | KB | 1 |
| 21784631 | 10.1016/j.bmcl.2011.06.036 | HepG2 | 1 |
Data from ChEMBL 36 via Core Engine