Compound Detail
CHEMBL185149
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Basic Information
| ChEMBL ID | CHEMBL185149 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | YNCKRHJTVVVVJZ-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
413.3
MW (Da)
3.39
ALogP
4
HBA
1
HBD
59.4
PSA (Ų)
0.84
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 7.02
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| D(4) dopamine receptor CHEMBL219 | EC50 | 7.02 | 7.02 | 96.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| D(4) dopamine receptor | EC50 | = | 96.0 | nM | 7.02 | Agonist activity was calculated in calcium flux assay using HEK293 cells co-tran... | 15380206 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 15380206 | 10.1016/j.bmcl.2004.07.068 | D(4) dopamine receptor | 4 |
Data from ChEMBL 36 via Core Engine