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Compound Detail

CHEMBL1880565

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CCCCCCNC(=O)O[C@H]1Cn2c(=O)n(CCCCCC)c(=O)n2[C@@H]2CN(S(=O)(=O)c3ccc(C)cc3)C[C@]12O

Basic Information

ChEMBL ID CHEMBL1880565
Phase Preclinical
Structure Type MOL
InChI Key IRLGTVAJOSFOAX-FMGHJNRGSA-N
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names

Molecular Properties

593.8
MW (Da)
2.37
ALogP
10
HBA
2
HBD
144.9
PSA (Ų)
0.34
QED
1
Ro5 Violations
13
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C28H43N5O7S
MW 593.75
Aromatic Rings 2
Heavy Atoms 41
NP-Likeness -0.34

Activity Summary

IC50 1 meas. best 4.99

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Unchecked
CHEMBL612545
IC50 4.99 4.99 10338.0 1

Activity Data Samples

Top measurements by pChEMBL value

Target Type Rel. Value Units pChEMBL Assay PubMed
Unchecked IC50 = 10338.0 nM 4.99 PubChem BioAssay. QFRET-based biochemical high throughput dose response assay to... -

Data from ChEMBL 36 via Core Engine