Compound Detail
CHEMBL188155
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Basic Information
| ChEMBL ID | CHEMBL188155 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | WYHUXLZANWVNPS-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
358.6
MW (Da)
5.28
ALogP
2
HBA
2
HBD
24.4
PSA (Ų)
0.33
QED
1
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 6.24
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Transient receptor potential cation channel subfamily V member 1 CHEMBL5102 | Ki | 6.24 | 6.24 | 580.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Transient receptor potential cation channel subfamily V member 1 | Ki | = | 580.0 | nM | 6.24 | In vitro binding affinity for rat TRPV1 expressed in CHO cells using [3H]-RTX | 16005215 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 16005215 | 10.1016/j.bmcl.2005.06.009 | Transient receptor potential cation channel subfamily V member 1 | 3 |
Data from ChEMBL 36 via Core Engine