Compound Detail
CHEMBL188175
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL188175 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | WEFLTDWSDJBWTM-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
394.2
MW (Da)
2.23
ALogP
4
HBA
0
HBD
88.2
PSA (Ų)
0.44
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 7.7
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Androgen receptor CHEMBL3072 | Ki | 7.7 | 7.7 | 20.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Androgen receptor | Ki | = | 20.0 | nM | 7.7 | Inhibition of rat prostate cytosolic androgen receptor | 15454212 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 15454212 | 10.1016/j.bmcl.2004.08.031 | Androgen receptor | 1 |
Data from ChEMBL 36 via Core Engine