Compound Detail
CHEMBL1883146
ACEPROMAZINE MALEATE Enter ChEMBL ID:
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Basic Information
| ChEMBL ID | CHEMBL1883146 |
| Name | ACEPROMAZINE MALEATE |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | FQRHOOHLUYHMGG-BTJKTKAUSA-N |
| Parent Compound | CHEMBL39560 |
| Active Moiety | CHEMBL39560 |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
4
Publications
2
Known Names
Molecular Properties
326.5
MW (Da)
4.44
ALogP
4
HBA
0
HBD
23.6
PSA (Ų)
0.76
QED
0
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Chirality | Achiral |
Activity Summary
IC50 1 meas. best 4.94
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | IC50 | 4.94 | 4.94 | 11383.5 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | IC50 | = | 11383.52 | nM | 4.94 | PubChem BioAssay. insulin secretion from INS-1E cells in the presence of 5 mM gl... | - |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| - | 10.6019/CHEMBL4495565 | SARS-CoV-2 | 2 |
| - | 10.1101/2020.04.03.023846 | SARS-CoV-2 | 1 |
| - | 10.21203/rs.3.rs-23951/v1 | SARS-CoV-2 | 1 |
| - | 10.6019/CHEMBL4495564 | Replicase polyprotein 1ab | 1 |
Data from ChEMBL 36 via Core Engine