Compound Detail
CHEMBL189653
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Basic Information
| ChEMBL ID | CHEMBL189653 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | YVDKIOCGSQYBND-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
473.4
MW (Da)
5.01
ALogP
5
HBA
1
HBD
57.7
PSA (Ų)
0.56
QED
1
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 6.1
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Melanin-concentrating hormone receptor 1 CHEMBL344 | IC50 | 6.1 | 6.1 | 790.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Melanin-concentrating hormone receptor 1 | IC50 | = | 790.0 | nM | 6.1 | Inhibition of Melanin-concentrating hormone 1 receptor expressed in CHO cells | 15267235 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 15267235 | 10.1021/jm040762v | Melanin-concentrating hormone receptor 1 | 1 |
Data from ChEMBL 36 via Core Engine