Compound Detail
CHEMBL190811
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL190811 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | BCQUNHBYUCGDMW-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
526.7
MW (Da)
5.62
ALogP
8
HBA
1
HBD
103.2
PSA (Ų)
0.27
QED
2
Ro5 Violations
10
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 8.15
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Type-2 angiotensin II receptor CHEMBL4607 | Ki | 8.15 | 8.15 | 7.1 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Type-2 angiotensin II receptor | Ki | = | 7.1 | nM | 8.15 | Displacement of [125I]-Ang II from pig uterus membrane angiotensin II type 2 (AT... | 15537354 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 15537354 | 10.1021/jm049715t | Angiotensin II receptor (AT-1) type-1 | 1 |
| 15537354 | 10.1021/jm049715t | Type-2 angiotensin II receptor | 1 |
| 15537354 | 10.1021/jm049715t | Unchecked | 1 |
Data from ChEMBL 36 via Core Engine