Compound Detail
CHEMBL190820
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Basic Information
| ChEMBL ID | CHEMBL190820 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | URHNZTIRUNVECH-WCWDXBQESA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
460.4
MW (Da)
5.85
ALogP
5
HBA
3
HBD
77.0
PSA (Ų)
0.19
QED
1
Ro5 Violations
6
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 2 meas. best 6.1
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| HFF CHEMBL614071 | EC50 | 6.1 | 5.53 | 800.0 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| HFF | EC50 | = | 800.0 | nM | 6.1 | Effective concentration required to inhibit vaccinia virus plaque formation in h... | 15828843 |
| HFF | EC50 | = | 11000.0 | nM | 4.96 | Effective concentration required to inhibit cowpox virus plaque formation in hum... | 15828843 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 15828843 | 10.1021/jm049147h | HFF | 6 |
Data from ChEMBL 36 via Core Engine