Compound Detail
CHEMBL1910059
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL1910059 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | PASBFQMDQRGJBH-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
4
Publications
0
Known Names
Molecular Properties
234.4
MW (Da)
3.31
ALogP
1
HBA
2
HBD
24.1
PSA (Ų)
0.77
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 5.62
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| B16 CHEMBL381 | IC50 | 5.62 | 5.62 | 2400.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| B16 | IC50 | = | 2400.0 | nM | 5.62 | Inhibition of alpha-MSH -stimulated melanogenesis in mouse B16 cells assessed as... | 21978680 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 21978680 | 10.1016/j.bmcl.2011.09.024 | Tyrosinase | 2 |
| 21978680 | 10.1016/j.bmcl.2011.09.024 | B16 | 2 |
| 28085281 | 10.1021/acs.jmedchem.6b01166 | D-3-phosphoglycerate dehydrogenase | 1 |
| 35636649 | 10.1016/j.bmcl.2022.128822 | Unchecked | 1 |
Data from ChEMBL 36 via Core Engine