Compound Detail
CHEMBL1923771
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Basic Information
| ChEMBL ID | CHEMBL1923771 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | RXMUZCZLPMFXFQ-UHFFFAOYSA-N |
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
410.6
MW (Da)
4.95
ALogP
5
HBA
3
HBD
79.2
PSA (Ų)
0.32
QED
0
Ro5 Violations
17
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 2 meas. best 6.77
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Cannabinoid receptor 1 CHEMBL218 | Ki | 6.77 | 6.77 | 170.0 | 1 |
| Cannabinoid receptor 2 CHEMBL253 | Ki | 6.72 | 6.72 | 190.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Cannabinoid receptor 1 | Ki | = | 170.0 | nM | 6.77 | Displacement of [3H]CP55940 from human CB1 receptor expressed in human HEK293 ce... | 22044209 |
| Cannabinoid receptor 2 | Ki | = | 190.0 | nM | 6.72 | Displacement of [3H]CP55940 from human CB2 receptor expressed in human HEK293 ce... | 22044209 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 22044209 | 10.1021/jm200529h | Cannabinoid receptor 1 | 1 |
| 22044209 | 10.1021/jm200529h | Cannabinoid receptor 2 | 1 |
Data from ChEMBL 36 via Core Engine