Compound Detail
CHEMBL1928023
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Basic Information
| ChEMBL ID | CHEMBL1928023 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | PCEDMSXAUCMJBA-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
388.5
MW (Da)
5.43
ALogP
5
HBA
0
HBD
57.3
PSA (Ų)
0.43
QED
1
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 6.05
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | IC50 | 6.05 | 6.05 | 890.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | IC50 | = | 890.0 | nM | 6.05 | Inhibition of hypoxia-induced HIF-1 transcriptional activity by luciferase repor... | 21937231 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 21937231 | 10.1016/j.bmcl.2011.08.120 | Unchecked | 1 |
| 25996239 | 10.1021/jm502014h | NON-PROTEIN TARGET | 1 |
Data from ChEMBL 36 via Core Engine