Compound Detail
CHEMBL195005
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Basic Information
| ChEMBL ID | CHEMBL195005 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | GVEZNLXUGOVBIY-UHFFFAOYSA-O |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
321.5
MW (Da)
3.93
ALogP
3
HBA
1
HBD
38.3
PSA (Ų)
0.38
QED
0
Ro5 Violations
11
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Kd 2 meas. best 5.51
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Cyclic nucleotide-gated channel alpha-1 CHEMBL4907 | Kd | 5.51 | 5.39 | 3100.0 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Cyclic nucleotide-gated channel alpha-1 | Kd | = | 3100.0 | nM | 5.51 | Apparent dissociation constant against Cyclic nucleotide gated channel alpha 1 a... | 16134947 |
| Cyclic nucleotide-gated channel alpha-1 | Kd | = | 5400.0 | nM | 5.27 | Apparent dissociation constant against Cyclic nucleotide gated channel alpha 1 a... | 16134947 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 16134947 | 10.1021/jm0502485 | Cyclic nucleotide-gated channel alpha-1 | 2 |
Data from ChEMBL 36 via Core Engine