Compound Detail
CHEMBL195481
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Basic Information
| ChEMBL ID | CHEMBL195481 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | MQFXWSJWILEPHS-NKWVEPMBSA-N |
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
5
Publications
0
Known Names
Molecular Properties
202.1
MW (Da)
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 6.66
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Dipeptidyl peptidase 2 CHEMBL3976 | IC50 | 6.66 | 6.66 | 220.0 | 1 |
| Dipeptidyl peptidase 8 CHEMBL4657 | IC50 | 5.22 | 5.22 | 6000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Dipeptidyl peptidase 2 | IC50 | = | 220.0 | nM | 6.66 | Inhibitory concentration against human dipeptidylpeptidase 7 | 16084722 |
| Dipeptidyl peptidase 8 | IC50 | = | 6000.0 | nM | 5.22 | Inhibitory concentration against human dipeptidylpeptidase 8 using FP-TAMRA incu... | 16084722 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 16084722 | 10.1016/j.bmcl.2005.06.076 | Dipeptidyl peptidase 2 | 1 |
| 16084722 | 10.1016/j.bmcl.2005.06.076 | Dipeptidyl peptidase 4 | 1 |
| 16084722 | 10.1016/j.bmcl.2005.06.076 | Prolyl endopeptidase FAP | 1 |
| 16084722 | 10.1016/j.bmcl.2005.06.076 | Dipeptidyl peptidase 8 | 1 |
| 16084722 | 10.1016/j.bmcl.2005.06.076 | Dipeptidyl peptidase 9 | 1 |
Data from ChEMBL 36 via Core Engine