Compound Detail
CHEMBL1964945
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Basic Information
| ChEMBL ID | CHEMBL1964945 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | LLFSHORTUJRLHA-UFFVCSGVSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
444.3
MW (Da)
5.57
ALogP
7
HBA
1
HBD
80.7
PSA (Ų)
0.41
QED
1
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 6.8
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Voltage-gated inwardly rectifying potassium channel KCNH2 CHEMBL240 | EC50 | 6.8 | 6.8 | 160.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Voltage-gated inwardly rectifying potassium channel KCNH2 | EC50 | = | 160.0 | nM | 6.8 | PUBCHEM_BIOASSAY: Confirmation Dose Response screen for compounds that protect h... | - |
Data from ChEMBL 36 via Core Engine