Compound Detail
CHEMBL196732
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL196732 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | ITRDPYNINWIWLM-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
284.4
MW (Da)
5.09
ALogP
2
HBA
1
HBD
29.5
PSA (Ų)
0.80
QED
1
Ro5 Violations
6
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 4.89
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Androgen receptor CHEMBL3072 | IC50 | 4.89 | 4.89 | 12882.5 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Androgen receptor | IC50 | = | 12882.5 | nM | 4.89 | Inhibitory concentration against recombinant rat androgen receptor expressed in ... | 16134935 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 6267281 | 10.1021/jm00136a013 | Estrogen receptor | 1 |
| 16134935 | 10.1021/jm050403f | Androgen receptor | 1 |
Data from ChEMBL 36 via Core Engine