Compound Detail
CHEMBL1980854
GLAZIOVINE 🧪 Phase II
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🧪 Phase II
Basic Information
| ChEMBL ID | CHEMBL1980854 |
| Name | GLAZIOVINE |
| Phase | Phase II |
| Structure Type | MOL |
| InChI Key | PNJUPRNTSWJWAX-UHFFFAOYSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
3
Publications
3
Known Names
Molecular Properties
297.4
MW (Da)
2.27
ALogP
4
HBA
1
HBD
49.8
PSA (Ų)
0.86
QED
0
Ro5 Violations
1
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Chirality | Racemic |
Activity Summary
IC50 2 meas. best 5.1
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Hepatitis B virus CHEMBL613497 | IC50 | 5.1 | 5.1 | 8000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Hepatitis B virus | IC50 | = | 8000.0 | nM | 5.1 | Antiviral activity against HBV transfected Hep G2.2.15 cells assessed as inhibit... | 17723297 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 17723297 | 10.1016/j.bmcl.2007.08.027 | Hepatitis B virus | 2 |
| 17723297 | 10.1016/j.bmcl.2007.08.027 | Unchecked | 2 |
| 17723297 | 10.1016/j.bmcl.2007.08.027 | NON-PROTEIN TARGET | 1 |
Data from ChEMBL 36 via Core Engine