Compound Detail
CHEMBL198642
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Basic Information
| ChEMBL ID | CHEMBL198642 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | OEYHUXZATDICNL-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
376.2
MW (Da)
5.05
ALogP
4
HBA
2
HBD
59.2
PSA (Ų)
0.52
QED
1
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 5.27
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Platelet-derived growth factor receptor beta CHEMBL1913 | IC50 | 5.27 | 5.27 | 5420.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Platelet-derived growth factor receptor beta | IC50 | = | 5420.0 | nM | 5.27 | Inhibitory activity against PDGFRbeta kinase | 16366598 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 16366598 | 10.1021/jm050680m | Platelet-derived growth factor receptor beta | 1 |
Data from ChEMBL 36 via Core Engine