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Compound Detail

CHEMBL1991599

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Oc1ccc(/C=N/N2CCOCC2)c(O)c1O

Basic Information

ChEMBL ID CHEMBL1991599
Phase Preclinical
Structure Type MOL
InChI Key QMKCXPQTYPNSFR-KPKJPENVSA-N
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names

Molecular Properties

238.2
MW (Da)
0.47
ALogP
6
HBA
3
HBD
85.5
PSA (Ų)
0.51
QED
0
Ro5 Violations
2
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C11H14N2O4
MW 238.24
Aromatic Rings 1
Heavy Atoms 17
NP-Likeness -0.54

Activity Summary

IC50 2 meas. best 4.99

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Mannose-6-phosphate isomerase
CHEMBL2758
IC50 4.99 4.965 10336.2 2

Activity Data Samples

Top measurements by pChEMBL value

Data from ChEMBL 36 via Core Engine