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Compound Detail

CHEMBL2004884

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CCN(CC)c1ccc(/C=c2\sc3nc4ccccc4n3c2=O)c(O)c1

Basic Information

ChEMBL ID CHEMBL2004884
Phase Preclinical
Structure Type MOL
InChI Key WSDHPUOHJBWIOH-WQRHYEAKSA-N
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names

Molecular Properties

365.5
MW (Da)
3.01
ALogP
6
HBA
1
HBD
57.8
PSA (Ų)
0.60
QED
0
Ro5 Violations
4
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C20H19N3O2S
MW 365.46
Aromatic Rings 4
Heavy Atoms 26
NP-Likeness -1.66

Activity Summary

EC50 2 meas. best 5.56

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Troponin, cardiac muscle
CHEMBL2095202
EC50 5.56 5.56 2780.0 1
Unchecked
CHEMBL612545
EC50 4.84 4.84 14409.0 1

Activity Data Samples

Top measurements by pChEMBL value

Data from ChEMBL 36 via Core Engine