Compound Detail
CHEMBL2009370
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Basic Information
| ChEMBL ID | CHEMBL2009370 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | IIINLXGWSVXPIL-NTMALXAHSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
241.3
MW (Da)
1.96
ALogP
6
HBA
0
HBD
41.6
PSA (Ų)
0.77
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 6.82
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| NAD(+) hydrolase SARM1 CHEMBL4523350 | IC50 | 6.82 | 6.82 | 150.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| NAD(+) hydrolase SARM1 | IC50 | = | 150.0 | nM | 6.82 | Inhibition of StrepTag-tagged human SARM1 TIR (561 to 724 residues) expressed in... | - |
Data from ChEMBL 36 via Core Engine