Compound Detail
CHEMBL202915
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL202915 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | CZYFKRKYUWJFNS-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
294.4
MW (Da)
2.44
ALogP
2
HBA
1
HBD
63.4
PSA (Ų)
0.88
QED
0
Ro5 Violations
1
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 5.53
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| 17-beta-hydroxysteroid dehydrogenase type 3 CHEMBL4234 | IC50 | 5.53 | 5.53 | 2980.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| 17-beta-hydroxysteroid dehydrogenase type 3 | IC50 | = | 2980.0 | nM | 5.53 | Inhibition of 17beta-HSD3 by SEAP assay | 16386902 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 16386902 | 10.1016/j.bmcl.2005.12.039 | 17-beta-hydroxysteroid dehydrogenase type 3 | 2 |
Data from ChEMBL 36 via Core Engine