Compound Detail
CHEMBL2029517
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Basic Information
| ChEMBL ID | CHEMBL2029517 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | AUDPELUZZOKGLM-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
246.3
MW (Da)
2.79
ALogP
3
HBA
1
HBD
45.8
PSA (Ų)
0.72
QED
0
Ro5 Violations
1
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 3.91
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| 3-phosphoinositide-dependent protein kinase 1 CHEMBL2534 | IC50 | 3.91 | 3.91 | 122000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| 3-phosphoinositide-dependent protein kinase 1 | IC50 | = | 122000.0 | nM | 3.91 | Competitive inhibition of PDK1 using [gamma-33P]-ATP as substrate after 30 mins ... | 22591730 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 22591730 | 10.1016/j.bmcl.2012.04.080 | 3-phosphoinositide-dependent protein kinase 1 | 1 |
Data from ChEMBL 36 via Core Engine